I have all of the new HTC devices in front of me, yet I struggle with the same question.
Personally, I love the size and build quality of the HTC One S (which I've unlocked for use on AT&T), but I hold back on carrying it as my daily driver because of the small (1,650 mAh) battery and non-HD display.
The HTC One X is a really nice device with 4G LTE support, but I don't care for the design. The rounded sides, curved display, and polycarbonate shell make the device feel a bit too toy-like for me.
I absolutely love the HTC EVO 4G LTE - the larger 2,000 mAh battery and design are near-perfect for my taste, and I'd carry it as my primary device (until the Galaxy S III, at least) if Sprint's 3G data speeds weren't so atrocious. Besides that, it's my favorite Android phone on the market at the moment.
I don't care for the design of the HTC DROID Incredible 4G LTE, but it'll be a decent option when it launches on Verizon "soon" (though I'm sure Big Red customers are clamoring for an official One device).
HTC's One V is cute, but it's a little bit too mid-range for me. Still, an awesome phone that I'm excited to see coming to the States in the next few months.
Which one is the all-around best? Obviously, it depends on your usage patterns, but it's a tough call at any rate. I feel your pain. If you had to make the choice, which one would you carry? Cast your vote and hit the comments with your thoughts!